Various yellow bananas filling frame
Mayukh Saha
Mayukh Saha
May 16, 2024 ·  2 min read

The World’s First GMO Bananas are Approved for Export to the U.S.

For over half a century, a devastating fungal disease has loomed over the banana industry. The Gros Michel banana, once the world’s dominant variety, was nearly wiped out by the Fusarium fungus. Now, the same threat hangs over the Cavendish banana, the world’s most popular fruit, and a multi-billion dollar industry. This is where GMO bananas are coming in.

A Resistant Cavendish GMO Banana

Professor James, along with the new GMO bananas, developed by the team he leads.
Image Credits: Queensland University of Technology

Scientists at Queensland University of Technology (QUT) in Australia have been working for two decades to develop a solution. Their answer: a genetically modified Cavendish banana resistant to the deadly fungus, known as Panama disease Tropical Race 4 (TR4). After extensive research and field trials, they’ve submitted their creation, QCAV-4, to regulatory authorities for approval.

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When Can We Get Our Hands On It?

Professor James Dale explaining his team's GMO Bananas.
Image Credits: QUT

This approval process will involve a detailed examination of the QCAV-4 gmo banana’s molecular, chemical, and nutritional composition. If successful, it would be the first-ever genetically modified whole fruit approved in Australia and the world’s first GM Cavendish banana plant.

The Threat of Panama Disease TR4

QUT's James Dale with grown QCAV-4 banana plants, at the QUT facility in the Northern Territory
Image Credits: QUT

Panama disease TR4 is a soil-borne fungus that can stay in the ground for decades, destroying banana crops and livelihoods for generations,” explains James Dale, a QUT professor and leading researcher on the project. This disease has already ravaged Cavendish plantations worldwide, and its continued spread could cripple the global export industry.

Overcoming The Cavendish Vulnerability

Close up shot of group of bananas
Credit: Shutterstock

The Cavendish banana’s vulnerability stems from its lack of sexual reproduction. Unlike many other plants, it cannot create genetic diversity naturally. Instead, it’s propagated through clones, creating fields of genetically identical plants. This lack of diversity makes the Cavendish highly susceptible to a single disease like TR4. The fungus attacks the banana plant through its roots, clogging the vessels that transport water and nutrients. This causes the plant to wilt and ultimately die. Unfortunately, once the fungus infects the soil, there’s no way to eradicate it with pesticides.

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A Hopeful Future for The GMO Banana

From left: The wild banana plant, the Cavendish plant and the QCAV-4 banana plant
Image Credits: QUT

The QCAV-4 gmo banana incorporates a single gene, RGA2, from a wild Southeast Asian banana that naturally resists TR4 infection. While Cavendish bananas already possess this gene, it’s dormant. The QCAV-4 modification activates this gene, enabling the plant to fight off the fungus.

While commercial production and consumption of QCAV-4 gmo bananas are still a ways off, its approval would provide a crucial safety net for the Cavendish variety. This genetically modified banana could prevent a repeat of Gros Michel’s demise and ensure the continued availability of this beloved fruit.

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