Jade Small
Jade Small
November 20, 2024 ·  4 min read

11 Medications That Can Cause Shaky Hands

Shaky hands, or tremors, can be unsettling and often raise concerns about conditions like Parkinson’s disease. However, there are numerous reasons your hands may tremble, and one common cause is medication. In this article, we’ll explore 11 medications that may lead to shaky hands and provide insights into what you can do if you’re experiencing this issue.

Understanding the Causes of Shaky Hands

Tremors can arise from various health conditions affecting the brain and nervous system. They can also be a side effect of certain medications. In some cases, tremors may occur when a health condition isn’t properly managed or as a symptom of the condition itself. Common causes include Parkinson’s disease, multiple sclerosis, strokes, anxiety, and thyroid imbalances. While it’s natural to be concerned, medications can also be the culprit.

1. Beta-Agonist Inhalers

Beta-agonist inhalers, prescribed for asthma and chronic lung conditions, are a well-known cause of shaky hands. Medications like albuterol (Ventolin HFA) and salmeterol (Serevent Diskus) can cause tremors when first used. This side effect typically improves after a few days of use, but it occurs because these inhalers affect muscle function in the body.

2. Amiodarone

Amiodarone, used to treat abnormal heart rhythms, can sometimes lead to tremors. This medication affects the nervous system and may also cause peripheral neuropathy, leading to shaky hands. While less common with lower doses used today, tremors were more frequently seen in the past with higher doses.

3. Tricyclic Antidepressants

Tricyclic antidepressants (TCAs), including amitriptyline and nortriptyline, are often used for depression and nerve pain. Although the research on TCAs and tremors is mixed, these medications can potentially worsen pre-existing tremors, especially if taken in high doses. If you’re taking a TCA, it’s important to discuss any side effects, including tremors, with your doctor.

4. Antidepressants (SSRIs and SNRIs)

Selective serotonin reuptake inhibitors (SSRIs) like fluoxetine (Prozac) and serotonin and norepinephrine reuptake inhibitors (SNRIs) such as duloxetine (Cymbalta) can also cause tremors. This side effect may be linked to serotonin syndrome, a rare but serious condition that can occur when serotonin levels become too high. Always inform your healthcare provider about any other medications you’re taking to help avoid interactions that could increase the risk of tremors.

5. Lithium

Lithium, used to treat bipolar disorder, is notorious for causing shaky hands. This tremor often occurs when starting the medication or adjusting the dosage. While some people experience only mild tremors, more severe cases could signal a dangerous condition known as lithium toxicity. Always consult with your provider if tremors become bothersome.

6. Valproate

Valproate medications, such as Depakote, are often prescribed for seizures and bipolar disorder. One common side effect is tremors, especially in older adults and women. These tremors can persist and may require a dose adjustment. If tremors become unmanageable, your doctor may suggest alternatives or additional treatments.

7. Antipsychotic Medications

Both typical and atypical antipsychotic medications, like thioridazine and olanzapine (Zyprexa), are used to treat schizophrenia and other psychiatric conditions. The tremors caused by typical antipsychotics occur because these drugs block dopamine receptors in the brain. If tremors persist, a doctor may adjust the medication or suggest alternatives to reduce the side effects.

8. Dopamine Blockers

Medications that block dopamine, such as metoclopramide (Reglan) used for GERD, can cause Parkinsonism symptoms, including tremors. These medications are generally prescribed for short periods, and long-term use may lead to persistent tremors. If you’re taking a dopamine blocker and experience shaky hands, it’s important to discuss switching medications with your healthcare provider.

9. Levothyroxine

Levothyroxine, a common treatment for hypothyroidism, can sometimes cause tremors by increasing thyroid hormone levels too much. This can overstimulate the nervous system, resulting in shaky hands. If you’re experiencing tremors while taking levothyroxine, your healthcare provider may adjust your dosage to alleviate the side effect.

10. Immunosuppressants

Medications like cyclosporine and tacrolimus, often prescribed after organ transplants, are known to cause shaky hands as a side effect. These drugs can affect the balance of chemical messengers in the brain, leading to tremors. If you’re on these medications, consult with your transplant specialist if tremors become an issue.

11. Bupropion

Bupropion, an antidepressant used for conditions like depression and smoking cessation, can cause tremors due to its effect on norepinephrine levels in the brain. If you notice shaky hands while taking bupropion, speak with your healthcare provider about adjusting your dose or considering a different treatment.

When to Seek Medical Advice

If you’re experiencing tremors or shaky hands, it’s important to talk to your doctor. They can help determine whether your medication is the cause or if another health condition is at play. If medication is the culprit, your doctor may suggest reducing your dose or switching to a different drug to resolve the tremors.

In conclusion, while shaky hands can be unsettling, they are often a temporary side effect of medication. Understanding which medications are most likely to cause tremors can help you and your healthcare provider find a solution. Always consult with your doctor before making any changes to your treatment plan.

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